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Some of the findings include the following: In a 2022 trial, subjects taking 1,000mg of urolithin A exhibited clinically meaningful improvements in their aerobic endurance and physical performance when compared to subjects who took either 500mg or a placebo.5 A separate 2022 trial examined the effects of 1,000mg urolithin A versus placebo in older adults after four months of daily supplementation

For more information about the innate immune response, see the article on Inflammation

Hepatitis is typically anicteric and elevated liver enzymes may take months to resolve completely.15,30,33 The second most frequently affected organ is the kidney, ranging from mild acute kidney injury to severe interstitial nephritis, resulting in permanent end-stage kidney disease

It plays a vital role in maintaining nerve health, improving metabolic functions, and supporting red blood cell formation

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